Yellow fever

- caused by flavivirus
- confined in Africa and South America
- transmitted by A.africanus (Africa) and Haemagogus (America)
- severe flu like illness with high grade fever, epigastric discomfort, relative bradycardia (Faget's sign) followed by an apparent recovery
- following the apparent recovery, patient develops high fever, jaundice, hepatomegaly, ecchymosis, gum bleeding, hematemesis and melena.
- mortality up to 40%
- treatment: supportive