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Sunday, 30 October 2011

Malignant melanoma

Clinical criteria for diagnosis (ABCDE)

A: Asymmetry of mole
B: Border irregularity
C: Colour variegation
D: Diameter more than 6mm
E: Evolving lesion with changes over time



Clarke's level (reflects level of invasion through dermis)
I : not invaded pass basement membrane
II: involvement of superficial dermis
III: involvement of deep dermis
IV: involvement of subcutis

Breslow's thickness

Tumor DepthApproximate 5 year survival
<1 mm95-100%
1 - 2 mm80-96%
2.1 - 4 mm60-75%
>4 mm50%

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