- caused by deficiency of apoliproprotein E (ligand for chylomicron)
- characterised by increased LDL, triglyceride and cholesterol, decreased HDL
- have elevation of IDL, a VLDL remnant
- diagnosed by lipoprotein electrophoresis or genotyping of apoprotein E
- also presents with tuboeruptive xanthoma
6 comments:
Which type of dyslipaedemia carries higher risk of cvs complication? Familial hypercholeterolemia vs type III hyperlipid?
Which one will increase cvs risk more? Type III hyperlipid vs familial hypercholesterol?
Familial hypercholesterolemia associated with premature CVS disease. Caused by LDL receptor dysfunction.Less common than familial combined hyperlipidemia.
Silly I know but -
P III, with lumps on knee from loss of E.
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