- malignant plasma cell proliferative disorder
- typically presents in 7th/8th decade of life
- increased IgM paraprotein
- presented with weakness, weight loss, fatigue, hepatosplenomegaly, lymphadenopathy
- most common complication is hyperviscosity syndrome
- increased plasma volume due to large amount of paraprotein
- serum protein electrophoresis - 75% IgM are kappa
- no isotype suppression (normal IgG and IgA levels)
- bone marrow aspirate often hypocellular, but biopsy specimen often hypercellular and extensively infiltrated by lymphoid or plasmacytoid cells
- no treatment needed if asymptomatic
- treatment : plasmapheresis (for hyperviscosity), chemotherapy (chlorambucil or fludarabine)
8 comments:
Natural Treatment for Waldenstrom's Macroglobulinemia
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Waldenström's macroglobulinemia is a slow-growing, constant kind of lymphoma. Waldenstrom’s Macroglobulinemia Natural Treatment might be prescribed to treat the disease. Herbs Solutions By Nature are offering Cremeton, an Herbal Supplements made out of 100% natural herbs for Waldenstrom’s Macroglobulinemia Herbal Treatment.
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If you have Waldenstrom's Macroglobulinemia, your bone marrow produces too many irregular white blood cells that troop out healthy blood cells. The irregular white blood cells produce a protein that accumulates in the blood, impairs circulation and causes complications. Natural Remedies for Waldenstrom's Macroglobulinemia is careful a type of non-Hodgkin's lymphoma. It's occasionally called lymphoma.
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