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Thursday 29 December 2011

Huntington's disease

- autosomal dominant (full penetrance)
- prevalence: 5:100,000
- a trinucleotide repeat disorder (CAG repeat)
- chromosome 4
- marked loss of neurones in the caudate nucleus and putamen
- increase in protein Huntingtin (polyglutamine)
- dementia, ataxia, abnormal choreiform movements, ophthalmoplegia
- diagnosis by DNA analysis
- treatment: phenothiazine for symptomatic control

1 comment:

MATINA said...

I was diagnosed as HEPATITIS B carrier in 2013 with fibrosis of the
liver already present. I started on antiviral medications which
reduced the viral load initially. After a couple of years the virus
became resistant. I started on HEPATITIS B Herbal treatment from
ULTIMATE LIFE CLINIC (www.ultimatelifeclinic.com) in March, 2020. Their
treatment totally reversed the virus. I did another blood test after
the 6 months long treatment and tested negative to the virus. Amazing
treatment! This treatment is a breakthrough for all HBV carriers.