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Saturday 17 December 2011

Clinical drug trials

Phase I
- to establish the human toxicity of a new drug by delivering carefully selected increase doses to fit patients with incurable diseases

Phase II
- to establish the antitumor activity of a drug against a particular tumor in fit patients with incurable diseases

Phase III
- to compare new drug with the best conventional therapy usually by a prospective randomised controlled trials

Phase IV
- to establish the drug efficiency in the adjuvant setting and are use to determine the long term side effects

1 comment:

MATINA said...

I was diagnosed as HEPATITIS B carrier in 2013 with fibrosis of the
liver already present. I started on antiviral medications which
reduced the viral load initially. After a couple of years the virus
became resistant. I started on HEPATITIS B Herbal treatment from
ULTIMATE LIFE CLINIC (www.ultimatelifeclinic.com) in March, 2020. Their
treatment totally reversed the virus. I did another blood test after
the 6 months long treatment and tested negative to the virus. Amazing
treatment! This treatment is a breakthrough for all HBV carriers.