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Tuesday 13 December 2011

Hemolytic uremic syndrome (HUS)

- characterised by MAHA (microangiopathic hemolytic anemia), thrombocytopenia, and acute kidney injury
- diarrhea associated HUS is associated with E.coli strain O157 (produces verocytotoxin which has A unit which is pathogenic and B unit which facilitate entry of A unit into endothelium)
- non diarrhea HUS is associated with factor H deficiency which is treated with plasmapheresis or plasma infusion
- sporadic cases of HUS is associated with pregnancy, SLE, scleroderma, malignant hypertension, metastatic cancer and HIV
- pneumococcus associated HUS is a rare complication of Strep.pneumoniae infection (antibodies to Thomsen antigen)

1 comment:

MATINA said...

I was diagnosed as HEPATITIS B carrier in 2013 with fibrosis of the
liver already present. I started on antiviral medications which
reduced the viral load initially. After a couple of years the virus
became resistant. I started on HEPATITIS B Herbal treatment from
ULTIMATE LIFE CLINIC (www.ultimatelifeclinic.com) in March, 2020. Their
treatment totally reversed the virus. I did another blood test after
the 6 months long treatment and tested negative to the virus. Amazing
treatment! This treatment is a breakthrough for all HBV carriers.