- 90% are women in age range 40-50 years
- serum AMA (anti-mitochondrial antibodies) subtype M2 in 95%
- associated with autoimmune disorders (Sjogren, scleroderma, thyroid disorder)
- pruritus is earliest symptom, preceding jaundice by a few years
- back pain can be prominent in advanced PBC due to osteomalacia from malabsorption or hepatic osteodystrophy. Osteoporosis is common.
- palmar xanthoma, tuberous xanthomas are seen
- raised ALP, increased serum cholesterol, raised IgM levels
- liver biopsy : granulomas surrounding bile ducts in early disease later progressing to cirrhosis
- treatment: ursodeoxycholic acid and replacement of vitamin A,D,E and K
- median survival overall is 7-10years, reduced to 2 years in presence of jaundice
2 comments:
So is possible that HIV Disease can be cured because I have been scammed so many times not until I came across this great man herbalist Dr Akhigbe who helped me at first I never believe all this comment and post about him and I was very sick because I have been infected with HIV/AIDS for the past two year,just last 2 months I keep reading the testimony about this man named Dr Akhigbe they said that the man is so powerful he have cured different type of diseases, I keep monitoring his post of some people about this man and I found out that he was real so I decided to give him a trial I contacted him for help and he said he was going to help me get my cure that all I needed to do was to send him money to prepare the medication after which it will be sent to me via DHL courier delivery services which I did to my greatest surprise the medication was sent to me he gave me instructions to follow on how to drink it that after three weeks I should go for check up,after taking the medicine and follow his instruction after three weeks I went back to the hospital for another test, at first I was shocked when the doctor told me that I was negative I ask the doctor to check again and the result was still the same negative that was how I free from HIV VIRUS at of the shock I decided to come and share my own testimony with you for those who think there is no cure for HIV VIRUS the cure as finally come' out stop doubting and contact Dr Akhigbe via email drrealakhigbe@gmail.com he will help you out you can also whatsApp him via +2348142454860 he is also perfect in curing DIABETICS,HERPES,HIV/AIDS, ;ALS, CANCER , MALARIA , BACTERIA DIARRJHEA, MENINGITIS,HEPATITIS A AND B,ASTHMA, HEART DISEASE, CHRONIC DISEASE. NAUSEA VOMITING OR DIARRHEA, KIDNEY DISEASE,, SCHIZOPHRENIA, LUPUS,EXTERNAL INFECTION, COMMON COLD, JOINT PAIN, OSTEOPOROSIS, RABIESRHEUMATISM, THYROID, GALLSTONE, COLD & FLU, CIRRHOSIS, DENGUE FEVER, EPILEPSY,STROKE,TUBERCULOSIS ,STOMACH DISEASE. ECZEMA, PROGERIA, EATING DISORDER, LOWER RESPIRATORY INFECTION. etc believe me that deadly disease is not longer a deadly sentence because dr akhigbe has the cure.the godfather of herbal root.email: drrealakhigbe@gmail.com whatsapp number. +2349010754824 website: https://drrealakhigbe.weebly.com
I was diagnosed as HEPATITIS B carrier in 2013 with fibrosis of the
liver already present. I started on antiviral medications which
reduced the viral load initially. After a couple of years the virus
became resistant. I started on HEPATITIS B Herbal treatment from
ULTIMATE LIFE CLINIC (www.ultimatelifeclinic.com) in March, 2020. Their
treatment totally reversed the virus. I did another blood test after
the 6 months long treatment and tested negative to the virus. Amazing
treatment! This treatment is a breakthrough for all HBV carriers.
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