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Wednesday 16 November 2011

Dopamine dysregulation syndrome

- a.k.a hedonistic dysregulation
- dysfunction of reward system in Parkinson's disease due to long exposure to dopamine replacement therapy
- characterised by self control problems such as addiction to medication, hypersexuality or gambling
- patient typically increase the amount of dopamine agonist although it will worsen their dyskinesia
- management: L-dopa dosage reduction

1 comment:

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