- X-linked, resulting from mutation of KAL1 gene which encodes anosmin-1
- occurs in 1:10,000 males
- results form disordered migration of gonadotrophin releasing hormone (GnRH) producing neurones into hypothalamus
- associated with anosmia, cleft palate, colour blindness, obesity, hypogonadotrophic hypogonadism
- treatment: male - hCG or testosterone restore pubertal development and secondary sexual characteristic. pulsed GnRH restore fertility ; female - cyclic estrogen and progesterone
1 comment:
I was diagnosed as HEPATITIS B carrier in 2013 with fibrosis of the
liver already present. I started on antiviral medications which
reduced the viral load initially. After a couple of years the virus
became resistant. I started on HEPATITIS B Herbal treatment from
ULTIMATE LIFE CLINIC (www.ultimatelifeclinic.com) in March, 2020. Their
treatment totally reversed the virus. I did another blood test after
the 6 months long treatment and tested negative to the virus. Amazing
treatment! This treatment is a breakthrough for all HBV carriers.
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