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Thursday, 17 November 2011

DMARDs side effects

Methotrexate
- marrow suppression, hepatic fibrosis, pneumonitis

Sulfasalazine
- leukopenia & thrombocytopenia, rash and macrocytosis

Hydroxychloroquine
- retinopathy

Gold 
- given by IM
- pancytopenia, lung fibrosis, cholestatic jaundice, glomerulonephritis, angioneurotic edema, exfoliative dermatitis

Penicillamine
- drug-induced lupus, proteinuria, loss of taste, pancytopenia

Leflunomide
- diarrhea, nausea, alopecia, rash

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