- FVIII is the most common target of antibody formation against specific clotting factor
- occurs predominantly in older adults (median age of 60)
- 50% idiopathic, others are associated with autoimmune disease, malignancy and pregnancy
- bleeding episodes occur commonly in soft tissues, GI or urinary tracts, haemarthrosis is rare
- prolonged APTT with normal PT
- Bethesda assay using FVIII deficient plasma as performed for inhibitor detection will confirm the diagnosis
- treatment with factor VIII is ineffective as the inhibitor has rapid activity
- bleeding is treated with recombinant activated factor VII or FEIBA(factor eight bypassing agent)
5 comments:
As a sign of gratitude for how my husband was saved from Hemorrhoids , i decided to reach out to those still suffering from this.
My husband suffered Hemorrhoids and it was really tough and heartbreaking for me because he was my all and the symptoms were terrible, we tried various therapies prescribed by our neurologist but none could cure him. I searched for a cure and i saw a testimony by someone who was cured and so many other with similar body problem, and he left the contact of the doctor who had the herbal cure to Hemorrhoids . I never imagined Hemorrhoids has a cure not until i contacted him and he assured me my husband will be fine. I got the herbal medication he recommended and my husband used it and in one months he was fully okay even up till this moment he is so full of life. Hemorrhoids has a cure and it is a herbal cure contact the doctor for more info on drwilliams098675@gmail.com on how to get the medication. Thanks for reading my testimony.
I am Sophie from Canada, I once suffered from a terrible and chronic hemophilia ,since 8 years now , the doctor told me there was no permanent cure i was given medications to slow down its progress, i constantly felt my health was deteriorating as i constantly go out of breath,and this illness was really terrible especially when am going out with my friends, i have this constant disorder for about 30 years, this was really a terrible illness ,on thin one day that i was going through the internet,and i came across a post of Mrs kate on how his husband was been cured from hemophilia through the help of Dr Williams herbal product, I contacted this herbal doctor via his email and explain everything to him and make purchase of his product,few days later he sent me the herbal medicine through courier service, when i received the herbal medicine, i used it for 1 months as prescribed by Dr Williams and i was totally cured within those week of usage,on thin now i have not experience any sign or characteristics again . for more information you can email him on drwilliams098675@gmail.com for help
Thanks to Dr Williams I am so happy today, my wife have been suffering from hemophilia for the past 8 years now, and i have spent a lot on western drugs which has all proved abortive, i have tried all means in life to get my wife out of this , but there was no answer until i decided to try herbal solution and i found Dr Williams online and i contacted him and after she took his medication as instructed, my wife is now completely cure from hemophilia within those week of usage, i am so much happy, thanks to Dr Williams for helping me get my wife life back again without any form of crisis, i promise to tell your name and good deeds to the whole world,if you have someone with hemophilia you can email him on drwilliams098675@gmail.com for more information .
ALL THANKS TO DR WILLIAMS WITH HIS HERB MY WIFE WAS COMPLETELY CURED FROM HEMOPHILIA .
Is my pleasure to comment on this site and i thank the admin of this site for his/her great work so far.one of the happiest moment in my life was when the doctor confirm that my wife is been free from this illness. this awesome moments makes me the happiest man on earth, I really don't know how to thank DR WILLIAMS for helping my wife get cured for over how many year of suffering from hemophilia. i came across DR Williams contact through a headline news on internet about how DR Williams help a woman to get cured of her hemophilia and so many other with similar body problem ,i contacted him and he told me how to get his herb,few day later he sent me the herbal portion which my wife take every morning for 28 days, and his medicine was able to cure her completely from hemophilia. and now she very mush okay without any side effects whatsoever, If you have hemophilia, you can contact him on his email address drwilliams098675@gmail.com for advice and for his product.
I would like to thank Ultimate Life Clinic for reversing my father's Amyotrophic Lateral Sclerosis (ALS). My father’s ALS condition was fast deteriorating before he started on the ALS Herbal medicine treatment from Ultimate Life Clinic. He was on the treatment for just 6 months and we never thought my father will recover so soon. He has gained some weight in the past months and he is able to walk with no support. You can reach them through there website www.ultimatelifeclinic.com
Post a Comment