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Saturday 28 April 2012

Gestational pemphigoid

- a.k.a herpes gestationalis (not associated with herpes virus)
- thought to be caused by autoantibodies which cross react to the basement membrane
- rash can appear anytime after 12th week of pregnancy or just after delivery
- typically starts at the navel area and then spread over the entire body
- diagnosis confirmed by skin biopsy using direct immunofluorescence
- treatment: corticosteroid ointment or oral steroid

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