- MPS are group of metabolic disorder caused by absence or malfunctioning of lysosomal enzymes needed to break down glycosaminoglycans (lysosomal storage disorder)
MPS type I (Hurler's syndrome)
- autosomal recessive
- cloudy cornea
- severe mental retardation
- gibbus
- coarse facies
- hepatosplenomegaly
MPS type II (Hunter's syndrome)
- X-linked
- clear cornea
- scoliosis, no gibbus
- less severe mental retardation
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