- gradual muscle weakness (mainly distal)
- weakness finger/wrist flexors out of proportion to finger/wrist extensors and shoulder abductors and weakness of knee extensors disproportionate to the hip flexors (quadriceps and long finger flexors)
- weakness of pharyngeal muscle causes dysphagia in 50%
- mild CK elevation
- muscle biopsy: inflammation and basophilic rimmed vacuoles with diagnostic filamentous inclusions and vacuoles on EM
- IBM is refractory to steroid and immunosuppresive agents
3 comments:
A ray of hope is on the horizon for patients facing the debilitating effects of the muscle-wasting disease inclusion body myositis. There is currently no Treatment of Inclusion Body Myositis, Translational Medicine, revealed that the drug deserves further study on its potential to slow patients' crippling debilitation.
http://www.herbs-solutions-by-nature.com/Inclusion-Body-Myositis.php
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