- characterised by recurrent venous/arterial thrombosis and miscarriages
- anticardiolipin antibodies and lupus anticoagulant positive
- paradoxical prolongation of APTT (due to antibody interfering the test), false positive syphilis test
- can cause hypoadrenalism (adrenal vein thrombosis)
- other features: migraine headache, chorea, seizures, transverse myelitis, GBS, livedo reticularis
- aspirin (if wish to get pregnant) or warfarin for patient with thrombotic syndromes
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