- 25% of dementia (second most common neurodegenerative disease)
- abnormal aggregation of synaptic protein (alpha-synuclein)
- characterized by Parkinsonian features, fluctuating cognitive loss and visual hallucinations
- Avoid neuroleptics (eg:Haloperidol) due to risk of inducing irreversible parkinsonism
- treatment :Rivastigmine (acetylcholinesterase inhibitor), Donezepil
No comments:
Post a Comment