Saturday, 31 December 2011

Nerve conduction studies

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Polymyositis - reduced amplitude and duration of motor units Motor neurone disease - fibrillation due to denervation Myasthenia gravis - d...

Cluster headache

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- a.k.a migrainous neuralgia - caused by superficial temporal artery smooth muscle hyperperactivity to 5HT - commoner in male - rapid ons...

Guillain Barre syndrome

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- a.k.a acute autoimmune inflammatory demyelinating polyneuropathy - segmental demyelination - 1-2/100,000/year - bimodal distribution wi...
1 comment:
Friday, 30 December 2011

Trypanosomiasis

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American trypanosomiasis (Chagas' disease) - caused by T.cruzi - spread by reduviids (triatomine bugs) - erythematous indurated nodul...
1 comment:
Thursday, 29 December 2011

Basic statistic (4)

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Paired student t test   - compare 2 paired groups of patients with parametric data (normal distribution) Wilcoxon test  - compare 2 paire...
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Huntington's disease

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- autosomal dominant (full penetrance) - prevalence: 5:100,000 - a trinucleotide repeat disorder (CAG repeat) - chromosome 4 - marked lo...
1 comment:

Motor neuron disease

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- cluster of major degenerative disease characterised by selective loss of neurons in motor cortex, cranial nerve nuclei, and anterior horn ...
11 comments:

Facioscapulohumeral dystrophy (FSHD)

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- autosomal dominant (gene locus 4q35) - onset 12-14 years old - initial weakness is seen in facial muscles, starting in orbicularis oculi...
1 comment:

Foster Kennedy syndrome

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- frontal lobe tumor (commonly meningioma in sphenoidal wings) - causing ipsilateral disc atrophy (compression) + contralateral disc swel...
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Idiopathic intracranial hypertension

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- a.k.a benign intracranial hypertension or pseudotumor cerebri - most common in obese young women between age 20-50 - headache (worse wi...