American trypanosomiasis (Chagas' disease)
- caused by T.cruzi
- spread by reduviids (triatomine bugs)
- erythematous indurated nodule (chagoma) at side of infection which may then scar
- fever, myalgia, rash, lymphadenopathy, hepatosplenomegaly, unilateral conjunctivitis, periorbital edema (Romana's sign), myocarditis, meningoencephalitis
- trypomastigotes seen or grown from blood in acute disease, serology in chronic disease
- treatment: nifurtimox, benznidazole
African trypanosomiasis (sleeping sickness)
- T.gambiense (slow, wasting illness), T.rhodesiense (rapidly progressive illness)
- spready by tsetse flies
- tender subcutaneous nodule (chancre) at site of infection
- 2 stages
i) haemolymphatic
- fever, rash, rigors, headache, hepatosplenomegaly, lymphadenopathy
- Winterbottom's sign (posterior cervical node enlargement)
ii) meningoencephalitic
- convulsion, agitation, confusion,apathy, depression, ataxia, dementia, hypersomnolence, coma
- treatment: suramin, melarsoprol
I was diagnosed as HEPATITIS B carrier in 2013 with fibrosis of the
ReplyDeleteliver already present. I started on antiviral medications which
reduced the viral load initially. After a couple of years the virus
became resistant. I started on HEPATITIS B Herbal treatment from
ULTIMATE LIFE CLINIC (www.ultimatelifeclinic.com) in March, 2020. Their
treatment totally reversed the virus. I did another blood test after
the 6 months long treatment and tested negative to the virus. Amazing
treatment! This treatment is a breakthrough for all HBV carriers.