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Thursday, 12 January 2012

Human leukocyte antigen (HLA)

- found on chromosome 6
- HLA corresponds to MHC class I (A,B and C)
- HLA corresponds to MHC class II (D)

HLA associations
- HLA DR2 : SLE
- HLA DR3 : autoimmune hepatitis, Sjogren syndrome
- HLA DR4 : Felty syndrome
- HLA DQ2 / DQ8 : coeliac disease
- HLA B27 : AS, Reiter's syndrome
- HLA Cw6 : psoriasis
- HLA B8 : myasthenia gravis
- HLA B5 / B51 : Behcet's disease

File:HLA.svg

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