Friday, 11 November 2011

Immune reconstitution inflammatory syndrome (IRIS)

- occurs in people who have been profoundly immunosuppressed and begin on HAART
- as immune system recovers, patient able to mount inflammatory response to a range of pathogens
- exacerbation of symptoms with new or worsening of clinical signs
Examples
- unusual mass lesions or lymphadenopathy associated with mycobacteria
- deteriorating radiological apperance associated with TB
- inflammatory retinal lesions associated with cytomegalovirus
- deteriorating liver function in chronic hepatitis B carrier
- vigorous vesicular eruption with herpes zoster

1 comment:


  1. I was diagnosed as HEPATITIS B carrier in 2013 with fibrosis of the
    liver already present. I started on antiviral medications which
    reduced the viral load initially. After a couple of years the virus
    became resistant. I started on HEPATITIS B Herbal treatment from
    ULTIMATE LIFE CLINIC (www.ultimatelifeclinic.com) in March, 2020. Their
    treatment totally reversed the virus. I did another blood test after
    the 6 months long treatment and tested negative to the virus. Amazing
    treatment! This treatment is a breakthrough for all HBV carriers.

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