- caused by Klebsiella granulomatis, encapsulated gram negative bacillus
- mode of transmission: sexual contact
- characteristic heaped up ulcerating lesion with prolific red granulation tissue
- rarely painful
- extension of primary infection to inguinal regions produces pseudo-bubo
- donovan bodies can be identified intracellularly in scrapings or biopsies of an ulcer
- treatment: doxycycline, bactrim or azithromycin
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