DMARDs side effects

Methotrexate

- marrow suppression, hepatic fibrosis, pneumonitis

Sulfasalazine

- leukopenia & thrombocytopenia, rash and macrocytosis

Hydroxychloroquine

- retinopathy

Gold 

- given by IM

- pancytopenia, lung fibrosis, cholestatic jaundice, glomerulonephritis, angioneurotic edema, exfoliative dermatitis

Penicillamine

- drug-induced lupus, proteinuria, loss of taste, pancytopenia

Leflunomide

- diarrhea, nausea, alopecia, rash