Wednesday, 5 October 2011

Waldenstrom macroglobulinemia

- a.k.a lymphoplasmacytoid lymphoma
- malignant plasma cell proliferative disorder
- typically presents in 7th/8th decade of life
- increased IgM paraprotein
- presented with weakness, weight loss, fatigue, hepatosplenomegaly, lymphadenopathy
- most common complication is hyperviscosity syndrome
- increased plasma volume due to large amount of paraprotein
- serum protein electrophoresis - 75% IgM are kappa
- no isotype suppression (normal IgG and IgA levels)
- bone marrow aspirate often hypocellular, but biopsy specimen often hypercellular and extensively infiltrated by lymphoid or plasmacytoid cells
- no treatment needed if asymptomatic
- treatment  : plasmapheresis (for hyperviscosity), chemotherapy (chlorambucil or fludarabine)

8 comments:

  1. Natural Treatment for Waldenstrom's Macroglobulinemia


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  2. Treatment for Waldenstrom's Macroglobulinemia disease will depend on the severity of your symptoms. You may not require treatment until you make side effects. Here Herbs Solutions By Nature suggests herbal treatments for Waldenstrom's disease.

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  3. Waldenström's macroglobulinemia is a slow-growing, constant kind of lymphoma. Waldenstrom’s Macroglobulinemia Natural Treatment might be prescribed to treat the disease. Herbs Solutions By Nature are offering Cremeton, an Herbal Supplements made out of 100% natural herbs for Waldenstrom’s Macroglobulinemia Herbal Treatment.

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  4. Natural Treatment for Waldenstrom’s Macroglobulinemia information about the Symptoms, Causes and Diagnosis. Natural Herbal Treatment for Waldenstrom’s Macroglobulinemia with Herbal Product Cremeton Natural Supplement for lymphoma, or cancer of the lymphatic system.
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  8. If you have Waldenstrom's Macroglobulinemia, your bone marrow produces too many irregular white blood cells that troop out healthy blood cells. The irregular white blood cells produce a protein that accumulates in the blood, impairs circulation and causes complications. Natural Remedies for Waldenstrom's Macroglobulinemia is careful a type of non-Hodgkin's lymphoma. It's occasionally called lymphoma.

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